μM.D.-ERL

Medical micro-Device Engineering Research Lab

at Michigan Tech

Research Publications

  • [In preparation/review] Z.I. Alshoug and A.R. Minerick, "Analysis of Lipemic Levels of Human Blood Samples Compared to Low-Density, High-Density, and Triglyceride Standards Using UV-Vis Spectroscopy," to be submitted, draft available Micromachines, Winter 2025-26.
  • [In preparation/review] J.L. Collins, A. Nelson, and A.R. Minerick, "Microdevice replication and design using a water-based acrylic polymer emulsion," to be submitted, draft available, Micromachines, Winter 2025-26
  • [In preparation/review] Z. Wang, L. J. McMillan, C. N. Hestekin, and A. R. Minerick, "Surface Isoelectric Focusing (sIEF) as an Auxiliary Tool for Rapid Glycoprotein Pre-analysis," to be submitted, draft available, Biomicrofluidics, Winter 2025-26.
  • [In preparation/review] H.Y. Lee, S. Habibi, J.A. Rogers, C. Kendrick, and A.R. Minerick, "Fabrication of photoresist SU-8 pyrolyzed carbon electrodes and their integration in a microfluidic hematocrit detection system," submitted under review, Sensors and Actuators B: Chemical 11/25.
  • [In preparation/review] Z. Wang and A.R. Minerick, "Surface Isoelectric Focusing (sIEF) for Hemoglobin Variants Separation with Narrow Range pH gradient," Under revision, will resubmit, Journal Chromatography A, Fall 2025.
  • Chapa, Isabel; Dykstra, Grace; Fungura, Asky; Krakhaleva, Natalia; Minerick, Adrienne; Liu, Yixin, “Aging the Imprint: Enhanced Performance of a Silver Prussian Blue Analogue–MIP Electrochemical Sensor for Sulfamethoxazole Detection in Milk,” ACS Sensors, 2025, https://doi.org/10.1021/acssensors.5c02385.
  • A. Tahmasebi, S. Habibi, J. Collins, R. An, E. Dehdashti, and A.R. Minerick, "pH Gradients in Spatially Non-uniform AC Electric Fields at or Below the Charging Frequency; A Study of Two Different Geometries and Electrode Passivation," Special Issue AC Electrokinetics in Microfluidic Devices, Micromachines 2023, 14(9), 1655; https://doi.org/10.3390/mi14091655.
  • R. An and A.R. Minerick, "Reaction-free concentration gradient generation in spatially non-uniform AC electric fields," Langmuir, 2022, 38, 19, 5977–5986. DOI: https://doi.org/10.1021/acs.langmuir.2c00013.
    Cover feature: View Cover
    ChemRxiv preprint (not peer-reviewed): An R, Minerick A.R. Reaction-free concentration gradient generation in spatially non-uniform AC electric fields. ChemRxiv. Cambridge: Cambridge Open Engage; 2022; This content was not peer-reviewed. https://doi.org/10.26434/chemrxiv-2022-k77ld-v2
  • S. Habibi, H.Y. Lee, H. Moncada-Hernandez, and A.R. Minerick, "Induction and Suppression of Cell Lysis in an Electrokinetic Microfluidic System," Electrophoresis, 2022, 1-15. https://doi.org/10.1002/elps.202100310 S. Habibi received Honorable Mention in the Best Student Paper Award for June 2022.
  • M.N. Hasan, R. An, A. Akkus, D. Akkaynak, A.R. Minerick, C. Kharangate, U.A. Gurkan, “Dynamic pH and thermal analysis of paper-based microchip electrophoresis,” Micromachines 2021,12(11), 1433; DOI: https://doi.org/10.3390/mi12111433
  • S. Habibi; P.U. Joshi; X. Mi; C. Heldt; A.R. Minerick, "Changes in membrane dielectric properties of porcine kidney cells provide insight into the antiviral activity of glycine" Langmuir 2020, 36, 29, 8344–8356. https://pubs.acs.org/doi/abs/10.1021/acs.langmuir.0c00175
  • S. Habibi, H.Y. Lee, H. Moncada-Hernandez, J. Gooding, and A.R. Minerick, "Impacts of low concentration surfactant on red blood cell dielectrophoretic responses," Biomicrofluidics, 2019: 13 (5), 054101 https://doi.org/10.1063/1.5113735.
  • J.L. Collins, H. Moncada-Hernandez, S. Habibi, Z. Wang, N. Bihari, C. Kendrick, P. Bergstrom, and A.R. Minerick, "Electrical and chemical characterizations of hafnium (IV) oxide films for biological lab-on-a-chip devices," Thin Solid Films, 2018: 662, pgs. 60-69, https://doi.org/10.1016/j.tsf.2018.07.024.
  • M. Khaksari, L.R. Mazzoleni, C. Ruan, P. Song, N.D. Hershey, R.T. Kennedy, M.A. Burns, and A.R. Minerick, “Detection and Quantification of Vitamins in Microliter Volumes of Biological Samples by LC-MS for Clinical Screening,” AIChE Journal, 2018: 64 (10), pgs. 3709-3718, http://dx.doi.org/10.1002/aic.16345.
  • Gao, Zhuangqiang; Ye, Haihang; Tang, Dianyong; Tao, Jing; Habibi, Sanaz; Minerick, Adrienne; Tang, Dianping; and Xia, Xiaohu, “Platinum Decorated Gold Nanoparticles with Dual Functionalities for Ultrasensitive Colorimetric In Vitro Diagnostics,” Nano Letters, 2017: 17(9), pgs. 5572-5579.
  • Z. Wang, C. Ivory, and A.R. Minerick, "Surface-Enabled Isoelectric Focusing (sIEF) with Carrier Ampholyte Type pH Gradient," Electrophoresis, 2017: 38 (20), pgs. 2565-2575. DOI: https://doi.org/10.1002/elps.201600565
  • M. Khaksari, L.R. Mazzoleni, C. Ruan, R.T. Kennedy, and A.R. Minerick, “Data Representing Two Separate LC-MS Methods for Detection and Quantification of Water-Soluble and Fat-Soluble Vitamins in Tears and Blood Serum,” Data in Brief, 2017. DOI: https://doi.org/10.1016/j.dib.2017.02.033
  • M. Khaksari, L.R. Mazzoleni, C. Ruan, R.T. Kennedy, and A.R. Minerick, “Determination of Water-Soluble and Fat-Soluble Vitamins in Tears and Blood Serum of Infants and Parents by Liquid Chromatography/Mass Spectrometry,” Experimental Eye Research, 2017: 155, pgs. 54–63, DOI: https://doi.org/10.1016/j.exer.2016.12.007.
  • H.Y. Lee, C. Barber, and A.R. Minerick, “Platinum electrode modification: Unique surface carbonization approach to improve performance and sensitivity”, Electrophoresis, 2015: 36 (15), pgs. 1666-1673. DOI: https://doi.org/10.1002/elps.201500227
  • C.J. Yang, C.-J. Wu, A.E. Ostafin, G. Thibaudeau, and A.R. Minerick, “Size, shell material, and medium conductivity dependence on dielectrophoretic behaviors of air core chitosan/poly-l-lysine shell nanoparticles,” Electrophoresis, 2015: 36 (7-8), pgs. 1002-1010. DOI: https://doi.org/10.1002/elps.201400315
  • H.Y. Lee, C. Barber, and A.R. Minerick, “Electrochemical hematocrit determination in a direct current microfluidic device”, Electrophoresis, 2015: 36 (7-8), pgs. 978-985. DOI: https://doi.org/10.1002/elps.201400466
  • R. An, K. Massa, D.O. Wipf, and A.R. Minerick, “Solution pH change in non-uniform AC electric fields at frequencies above the electrode charging frequency”, Biomicrofluidics, 2014, 8 (6): 064126 DOI: https://doi.org/10.1063/1.4904059
  • T.N.G. Adams, P.A. Turner, A.V. Janorkar, F. Zhao, and A.R. Minerick, Characterizing the Dielectric Properties of Human Mesenchymal Stem Cells and the Effects of Charged Elastin-like Polypeptide Copolymer Treatment, Biomicrofluidics 2014, 8 (5): 054109 DOI: https://doi.org/10.1063/1.4895756.
  • H. Xie, R. Tewari, H. Fukushima, J. Narendra, C. Heldt, J. King, and A.R. Minerick, “Development of a 3D graphene electrode dielectrophoretic device,” JoVE (Journal of Visualized Experiments), 2014, Issue 88, URL: http://www.jove.com/video/51696, DOI: https://doi.org/10.3791/51696
  • H.Y. Lee, C. Barber, and A.R. Minerick, “Improving electrokinetic microdevice stability by controlling electrolysis bubbles,” Electrophoresis, 2014: 35 (12-13), pgs. 1782–1789. DOI: https://doi.org/10.1002/elps.201400013
  • H. Moncada-Hernandez, E. Nagler, and A.R. Minerick, “Assessment of the particle-particle influence on the dielectrophoretic response of microparticles,” Electrophoresis, 2014: 35 (12-13), pgs. 1803–1813. DOI: https://doi.org/10.1002/elps.201300636
  • A. Gencoglu, and A.R. Minerick, “Electrochemical Detection Techniques in Micro- and Nanofluidic Devices,” Microfluidics and Nanofluidics, 2014: 17(5), pgs. 781-807 DOI: https://doi.org/10.1007/s10404-014-1385-z.
  • R. An, D.O. Wipf, and A.R. Minerick, “Spatially variant red blood cell crenation in alternating current non-uniform fields,” Biomicrofluidics, 2014, 8(2): 021803 DOI: https://doi.org/10.1063/1.4867557
  • T.N.G. Adams, K.M. Leonard, and A.R. Minerick, "Frequency Sweep Rate Dependence on the Dielectrophoretic Response of Polystyrene Beads and Red Blood Cells," Biomicrofluidics, 2013, 7(6): 064114. DOI: https://doi.org/10.1063/1.4833095
  • A.R. Minerick, “DC Dielectrophoresis in Lab-on-a-Chip Devices - Revised.” In: Li, Dongqing (ed). Encyclopedia of Micro- and Nanofluidics. 2nd Ed. Springer, Berlin Heidelberg New York, 2013.
  • A.R. Minerick, and G. Thibaudeau. “Detection Using Confocal Microscopy - Revised.” In: Li, Dongqing (ed). Encyclopedia of Micro- and Nanofluidics. 2nd Ed. Springer, Berlin Heidelberg New York, 2013.
  • C.L. Heldt, A.K. Sieloff, J.P. Merillat, A.R. Minerick, J.A. King, W.F. Perger, H. Fukushima, J. Narendra, “Stacked graphene nanoplatelet paper sensor for protein detection,” Sensors and Actuators B, 2013, 181:92-98 DOI https://doi.org/10.1016/j.snb.2013.01.041.
  • K.M. Leonard, and A.R. Minerick, "Explorations of ABO-Rh antigen expressions on erythrocyte dielectrophoresis: Changes in Cross Over Frequency,” Special Dielectrophoresis Issue of Electrophoresis, 2011, 32(15): 2512-2522. DOI https://doi.org/10.1002/elps.201100077.
  • A. Gencoglu, F. Camacho-Alanis, V. T. Nguyen, A. Nakano, A. Ros, and A. R. Minerick, “Quantification of pH Gradients and Implications in Insulator-Based Dielectrophoresis of Biomolecules”, Special Dielectrophoresis Issue of Electrophoresis, 2011, 32(15): 2436–2447. DOI: https://doi.org/10.1002/elps.201100090
  • S.K. Srivastava, A. Artemos and A. R. Minerick, “DC insulator-based dielectrophoretic characterization of erythrocytes: ABO-Rh human blood typing”, Special Dielectrophoresis Issue of Electrophoresis, 2011, 32(15): 2530–2540. DOI: https://doi.org/10.1002/elps.201100089
  • S.K. Srivastava, A.R. Minerick, J. Baylon-Cardiel, and B.H. Lapizco-Encinas. “A continuous DC-insulator dielectrophoretic sorter of microparticles”, Journal Chromatography A, 1218:13, p. 1780-1789, 2011. DOI: https://doi.org/10.1016/j.chroma.2011.01.082
  • S.K. Srivastava, A. Gencoglu, and A.R. Minerick, “DC insulator dielectrophoretic applications in microdevice technology: a review.” Analytical and Bioanalytical Chemistry, Volume 399, Issue 1, Page 301, 2011. DOI: https://doi.org/10.1007/s00216-010-4222-6
  • A. Gencoglu, and A.R. Minerick, "Chemical and Morphological Changes on Platinum Microelectrode Surfaces in AC and DC fields with Biological Buffer Solutions," Lab on a Chip, Volume 9, Issue 13, 2009. DOI: https://doi.org/10.1039/B820126A
  • S.K. Srivastava, P.R. Daggolu, S.C. Burgess, and A.R. Minerick, "Dielectrophoretic Characterization of Erythrocytes: Positive ABO Blood Types," Electrophoresis, Volume 29, Issue 24, Pages 5033-5046, 2008. DOI: https://doi.org/10.1002/elps.200800166 Won 1st place, Outstanding Paper in Swalm Chemical Engineering Department 2008
  • A.R. Minerick, "The Rapidly Growing Field of Micro and Nanotechnology to Measure Living Cells," Invited Perspective with Cover Figure, AIChE Journal, Volume 54, Issue 9, Pages 2230-2237, September 2008. DOI: https://doi.org/10.1002/aic.11615
  • A.R. Minerick, V.M. Ugaz, S. Murthy, J.P. Posner, "Review of Electrophoresis and BioMEMS in 2007: American Electrophoresis Society 24th Annual Meeting," J Capillary Electrophoresis and Microchip Technology, Volume 10, Issue 5/6, Pages 101-109, 2008.
  • A.R. Minerick, “DC Dielectrophoresis in Lab-on-a-Chip Devices.” In: Li, Dongqing (ed). Encyclopedia of Micro- and Nanofluidics. Springer, Berlin Heidelberg New York, 2008.
  • A.R. Minerick, and G. Thibaudeau. “Detection Using Confocal Microscopy.” In: Li, Dongqing (ed). Encyclopedia of Micro- and Nanofluidics. Springer, Berlin Heidelberg New York, 2008.
  • A.R. Minerick, and V.M. Ugaz. "BioMEMS and Electrophoresis in 2006: Review of the 23rd Annual Meeting of the American Electrophoresis Society," 1(2) #:021504 Biomicrofluidics, 2007.
  • B.P. Helmke, and A.R. Minerick. "Designing a Nano-Interface in a Microfluidic Chip to Probe Living Cells: Challenges and Perspectives," Proceedings of the National Academy of Science, 103(17), 6419-6424, 2006. DOI: https://doi.org/10.1073/pnas.0507304103
  • A.R. Minerick, R. Zhou, P. Takhistov, and H.-C. Chang. "Manipulation and Characterization of Red Blood Cells with Alternating Current Fields in Micro-Devices" Electrophoresis, 24(21): 3703-3717, 2003. DOI: https://doi.org/10.1002/elps.200305644
  • A.R. Minerick, H.-C. Chang, T.M. Hoagland, and K.R. Olson. "Dynamic synchronization analysis of venous pressure-driven cardiac output in rainbow trout," American Journal of Physiology – Regulatory, Integrative and Comparative Physiology 285 (4): R889-R896, 2003. DOI: https://doi.org/10.1152/ajpregu.00228.2003
  • A.R. Minerick, A. Ostafin, and H.-C. Chang. "Electrokinetic Transport of Red Blood Cells in Micro-Capillaries," Electrophoresis, 23, 2165-2173, 2002. DOI: https://doi.org/10.1002/1522-2683(200207)23:14<2165::AID-ELPS2165>3.0.CO;2-#

Book Chapters

  • T.N.G. Adams, C.J. Yang, J. Gress, N. Wimmer, and A.R. Minerick, “A Tunable Microfluidic Device for Drug Delivery,” Chapter in Advances in Microfluidics, ISBN 978-953-51-0106-2, Edited by Ryan T. Kelly, InTech Publishers, 2012. Reached 4,000 downloads in May 2017.
  • A.R. Minerick, “Particles in Microfluidic Systems”, Chapter in Microfluidic Devices in Nanotechnology: Fundamental Concepts, Edited by Challa Kumar Wiley, 2010.

Research Proceedings and Technical Articles

  • Rachel Cole, Samikhshak Gupta, Vijaya V. N. Sriram Malladi, Smitha Rao Hatti, and Adrienne Minerick, “Experimental-Based Investigation of Standing and Traveling Waves in a Petri Dish using Piezoelectric Actuation,” Proceedings of the International Modal Analysis Conference (IMAC), Paper No. 20629, Palm Springs, CA, USA, January 19–22, 2026.
  • Alshoug, Z.I., Fozilova, R., Flores, H., Mainville, M. D., Dwarakanath, S., Hinshaw, J., Gurkan, U. A., Galen, P., and Minerick, A. R., "Buffer Influence on pH Stability During Protein Separations in Paper Based Electrophoresis for Point-of-Care (POC) Devices.", IEEE EMBS Healthcare Innovations and Point of Care Technologies (HI-POCT) Conference, University of Arizona, Tucson, AZ, September 2024. (refereed)
  • R. A. Muhammad Noman Hasan, Asya Akkus, Adrienne Minerick, Umut Gurkan, "Fundamental Aspects of Paper-Based Electrophoresis MicroChip - pH Gradient," presented at the Summer Biomechanics, Bioengineering, and Biotransport Conference, Seven Springs, Pennsylvania, June 25 – 28, 2019.
  • C. Yang, Chun-Jen Wu, Agnes E. Ostafin and A.R. Minerick, “Dielectrophoretic Response of Perfluorooctyl bromide oil-core, Chitosan/Poly-L-lysine Shell Nanoparticles.” Particle-laden flows, Jeju International Conference on Multiphase Flow (ICMF) proceedings 2013. (not refereed)
  • ‘Ideas from CEE’ (Chemical Engineering Education Journal), Journal Clubs Encourage Graduate and Undergraduate Research Students to Critically Review the Literature,” in Summer 2011 issue of AIChE’s Education Division Newsletter.
  • Leonard, K.M., E. Rutan, S. Reeves, M. Walton, A. Pate, S. Thompson, and A.R. Minerick, “Dielectrophoretic Characterization of Red Blood Cells,” AIChE Annual Proceedings, 2008. (not refereed)
  • Srivastava, S.K., A. Pullen, and A.R. Minerick, “Insulator-based Dielectrophoretic Lab-on-a-Chip System for Erythrocytes,” AIChE Annual Proceedings, 2008. (not refereed)
  • Gencoglu, A. E.F. Cotton, S.A. Pullen, S. Thompson, B.S. Tosun, and A.R. Minerick, “Surface Chemistry and Morphology of Platinum Microelectrodes Subjected to a Dielectrophoretic Field,” AIChE Annual Proceedings, 2008. (not refereed)
  • "Innovations in Micro and Nanotechnology to Measure Living Cells.” AIChE Journal Highlight in Chemical Engineering Progress, Volume 104, No 9, Page 12, 2008.
  • Keshavamurthy, S.S. K.M. Leonard, S.C. Burgess, A.M. Minerick, “Direct Current Dielectrophoretic Characterization of Erythrocytes: Positive ABO Blood Types” NSTI-Nanotech, 2008, vol 2, 401-404.
  • Minerick, A.R., and V.M. Ugaz. "Preface to Special Topic: Papers from the 2006 Annual Meeting of the American Electrophoresis Society, San Francisco, CA.” 1(2) #021501 Biomicrofluidics, 2007.
  • Minerick, A.R. "Better Cellular Manipulations Through Electricity: Electroporation," American Electrophoresis Society Newsletter, 11(3), 2006.
  • Minerick, A.R. and R. Pethig, "Dielectrophoresis: Tools to Manipulate Cells in Microdevices," American Electrophoresis Society Newsletter, 10(3), 2005.
  • Minerick, A.R., K. King, P. Takhistov, A. Ostafin, and H.-C. Chang, “Electrophoretic Transport of Red Blood Cells in Micro-Capillaries,” AIChE Annual Proceedings, 2001. (not refereed)

Editorial Roles

  • Editorial Board Member for section 'B4: Point-of-Care Devices' MDPI Micromachines. 2023-present. Link
  • Guest Editor with Mark A. Burns and Sanaz Habibi, Biosensors Special Issue: Microfluidic Biosensors for Health Monitoring 2022 Link
  • Guest Editor with Victor Ugaz, AES Special Issue in Biomicrofluidics. BioMEMS and Electrophoresis in 2006: Review of the 23rd Annual Meeting of the American Electrophoresis Society Link

Media and Trade Publications

  • Photograph included in Nanowonder: Images of the Microscopic World, a juried exhibition of photographs taken by the Hitachi Scanning Electron Microscope (SEM).
  • Adrienne Minerick Recognized for Transformative Mentorship and Institutional Change Link
  • Q&A with MTU Diversity Award Winner Adrienne Minerick Link
  • Minerick, A.R. Interview on ASEE TV: Importance of Engineering Culture for Engineering of the Future June 2022 YouTube
  • Minerick, A.R. Interview on ASEE TV (Episode 3): July 2021 YouTube
  • Against the Grain by Pierre Home-Douglas Link Sept. 2021
  • Microfluidics Helps Engineers Watch Viral Infection in Real Time Link
  • MTU's Adrienne Minerick Elected to Lead Engineering Educators Link
  • Q&A with Bhakta Rath Winners Sanaz Habibi and Adrienne Minerick Link
  • Michigan Tech faculty earn honors for their innovation and dedication. Link
  • Minerick Shifts Gears as the New Dean of the School of Technology Link
  • NSF Funds Program to Recruit and Keep Diverse Faculty Link
  • Minerick, A.R. Interview on ASEE TV: Diversity Committee YouTube
  • From the Lab to the Marketplace: Michigan Tech Researchers Find Help at Home to Commercialize Their Discoveries Link
  • Michigan Tech names new dean Link
  • Alaina G. Levine, “From selfies to selfless: Managing multigenerational teams,” Link Sept 2017.
  • Michigan Tech News Release. Adrienne Minerick Chosen for STEM Leadership Fellowship Link
  • Michigan Tech News Release. Crybaby: The Vitamins in Your Tears Link
  • Michigan Tech News Release. Tech Wins Awards for Diversity Efforts in Engineering Education Link
  • Michigan Tech News Release. Model Designed to Promote Collaboration and Communications Link
  • Michigan Tech News Release. Adrienne Minerick Honored by AES Electrophoresis Society Link
  • Michigan Tech News Release. From the Lab to the Marketplace Link
  • Michigan Tech News Release. Minerick Named Associate Dean Link
  • Crain’s Detroit Business: Michigan Tech spinoff's device screens would-be donors' blood Link
  • AIChE ChEnected Interview: Adrienne Minerick on Diversity in Chemical Engineering. Link
  • Infant Tear Clinical Trial, Promotional Video by Portage Health. Link
  • Michigan Tech News Release. Adrienne Minerick Named AAAS Fellow Link
  • Michigan Tech News Release. Minerick to Present at NAE Symposium Link
  • TV6 evening news spot (regional), interview, “Michigan Tech research to revolutionize blood testing?” Link
  • Michigan Tech Techtube. Microdevices & Blood Typing. Link